'Green Chemistry' Guru Charting New Course for EPA Science

Paul Anastas.

The assistant administrator of U.S. EPA's Office of Research and Development and the agency's science adviser is a high-strung fast talker who in a recent interview orbited his sprawling office to play show and tell. His favorite prop is a large white board on which he has scribbled seemingly unrelated slogans -- such as "Strategic Imperatives!" and "4-D Matrix!"

But Anastas, 49, is no bug-eyed, wild-haired caricature of an eccentric genius. He is good-humored and friendly and has the carefully coiffed, buttoned-down look of a politician. He also chooses his words with care; he doesn't stray from the agency line and is mindful to heap praise on his bosses, EPA Administrator Lisa Jackson and President Obama.

To his supporters, Anastas is a creative, big-picture thinker. To his few detractors, he is too big picture, prone to straying from important day-to-day actions. Both sides know him as "the father of 'green chemistry,'" the design of alternative chemicals that pose no risk to human health or the environment.

Since Anastas and chemist John C. Warner penned the principles of green chemistry 20 years ago, the field has expanded rapidly and many believe it holds the solutions to chemical threats to public health and the environment.

Anastas' fans say he is capable of making monumental changes at EPA.

"Inventors are inherently impatient with the status quo," said Charlotte Brody, the director of chemicals, public health and green chemistry at the BlueGreen Alliance -- a partnership of labor and environmental groups. "He's done a very important piece of work in pushing against the limit of current regulatory frameworks. He is moving the agency from a vision of a country that is well regulated to a vision of the country that is sustainable."

Anastas grew up in Quincy, Mass., and holds on to a faint Boston accent and a devotion to the Red Sox. His boyhood home faced wetlands teeming with wildlife.

When he was still a boy, developers destroyed the wetlands to make room for what Anastas called "big glass insurance companies and banks." The buildings left a mark on Anastas.

"My dad was a high school biology teacher," he recalled during a recent interview at his office at EPA's Washington, D.C., headquarters. "He had this 8-year-old on his hands who was pretty upset. One of the things he said was, 'If you really care about something, you care enough to learn about it.'"

Anastas wrote an essay on the wetlands that received a presidential award from Richard Nixon in 1971. The award hangs in his EPA office.

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'Green Chemistry' Guru Charting New Course for EPA Science

"Instead of trying to design molecules so they could either treat or cure cancer," he said, "I'd like to make it so we design all molecules so that they never cause cancer or other toxic effects." By 1991, Anastas had published the 12 principles of



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